2018 ESMO DAY 3:结直肠癌看什么?

陈功医生

<h3>陈功</h3><h3>中山大学肿瘤医院</h3><h3> </h3> <h3><br /></h3><h3>2018年10月21日星期日,ESMO年会第三天,肠癌领域主要交流内容如下:</h3><h3><br /></h3><h3> </h3><h3><b style="color: rgb(237, 35, 8);">挑战专家专场(Challenge Your Expert session)</b></h3><h3><br /></h3><h3><b style="color: rgb(22, 126, 251);">主题:小肠腺癌</b></h3><h3><b style="color: rgb(22, 126, 251);">时间:2018-10-21, 08:00-09:00</b></h3><h3><b style="color: rgb(22, 126, 251);">地点:Hall B3, Room 22</b></h3><h3>形式:主题讲座+现场讨论</h3><h3><br /></h3><h3>该专场类似于"教授有约"专场,针对某一特殊临床问题进行讲座。小肠腺癌的处理,按照指南,是参照结肠癌来治疗的,但由于总体发病率很低,相对罕见,一般临床医生欠缺处理经验,因此,也是一个绝好的学习机会。</h3><h3> </h3><h3><br /></h3><h3><b style="color: rgb(237, 35, 8);">特别专场(Special Symposium)</b></h3><h3><br /></h3><h3><b style="color: rgb(22, 126, 251);">主题:mCRC的癌症精准医学(Precision cancer medicine in metastatic colorectal cancer)</b></h3><h3><b style="color: rgb(22, 126, 251);">时间:2018-10-21, 09:15-10:45</b></h3><h3><b style="color: rgb(22, 126, 251);">地点:Hall A2, Room 18</b></h3><h3>讲题:</h3><h3><br /></h3><h3>1 病理亚组和分子特征(Pathological subgroups and molecular characterisation)</h3><h3><br /></h3><h3>2 特殊(罕见)亚型的新型治疗方法(Novel therapeutic approaches for specific (rare) subtypes)</h3><h3><br /></h3><h3>3 免疫治疗:检查点抑制剂及其他(Immunotherapy: Checkpoint inhibitors and beyond)</h3><h3> </h3><h3><br /></h3><h3><b style="color: rgb(237, 35, 8);">ESMO临床实践指南专场1(ESMO Clinical Practice Guidelines 1)</b></h3><h3><br /></h3><h3><b style="color: rgb(22, 126, 251);">时间:2018-10-21, 10:45-11:15</b></h3><h3><b style="color: rgb(22, 126, 251);">地点:Hall A1, Room 15</b></h3><h3><b style="color: rgb(22, 126, 251);">主题:直肠癌的处理</b></h3><h3><br /></h3><h3>该专场以病例互动的形式来讲解ESMO指南,现场设有问卷调查</h3><h3> </h3><h3><br /></h3><h3><b style="color: rgb(237, 35, 8);">欧洲肿瘤护理学会专场-症状处理(EONS session- Symptom management)</b></h3><h3><b style="color: rgb(237, 35, 8);"><br /></b></h3><h3><b style="color: rgb(22, 126, 251);">时间:2018-10-21, 11:00-12:00</b></h3><h3><b style="color: rgb(22, 126, 251);">地点:HALL B4, Room 24</b></h3><h3>摘要:</h3><h3><br /></h3><h3>CN26- 生存的花费:卫生保健系统中能预测结直肠癌生存者生活质量的相关因素的混合方法探索研究(The Cost of Survival: A Mixed-Method Exploration of Healthcare-Related Factors Predicting Colorectal Cancer SurvivorsQuality of Life)</h3><h3>&nbsp;</h3><h3>CN53 直肠癌患者的生存保健:LARS(低位前切除术综合征)的痛苦(Rectal cancer survivorship: the struggle of the low anterior resection syndrome (LARS))</h3><h3>&nbsp;</h3><h3>该专场中最值得关注的就是CN53关于LARS处理的,低位直肠癌患者接受保肛手术(主要是低位前切除术,LAR)后经常出现一组排便异常症状群,称之为LARS,是以便急、便频和气便失禁等为主的一系列症状组成的综合征,在少部分患者也可能表现为便秘或排粪困难等症状,对患者生活质量带来很大困扰,部分患者因为无法耐受这种失常的排便功能而不得不行永久性造口。接受术前放化疗的患者,LARS发生几率更高。国内对此的研究、护理相对匮乏,国内同道值得好好学习参考。</h3><h3> </h3><h3><br /></h3><h3><b style="color: rgb(237, 35, 8);">壁报讨论专场:-结直肠癌2</b></h3><h3><b style="color: rgb(237, 35, 8);"><br /></b></h3><h3><b style="color: rgb(22, 126, 251);">时间:2018-10-21,16:45-17:45</b></h3><h3><b style="color: rgb(22, 126, 251);">地点:ICM, Room 14b</b></h3><h3>摘要:</h3><h3><br /></h3><h3>456PD ctDNA系列监测在结直肠癌残余转移灶检测、辅助化疗疗效评估和复发早期发现中的价值(Serial circulating tumor DNA analysis for detection of residual disease, assessment of adjuvant therapy efficacy and for early recurrence detection in colorectal cancer)</h3><h3>&nbsp;</h3><h3>457PD- 结直肠癌中的激酶融合:一个特殊的生物学亚群(Kinase Fusions in Colorectal Cancers: A Unique Biologic Subset)</h3><h3>&nbsp;</h3><h3>LBA24 局限性结直肠癌患者前瞻性分层的多组学分析(A Multi-Omic Analysis for Prospective Patient Stratification in Localised Colorectal Cancer (CRC).)</h3><h3><br /></h3><h3>458PD CALGB/SWOG 80405研究的因果模型分析揭示了mCRC中原发瘤相关的血管生成性驱动因素(Causal modeling of CALGB/SWOG 80405 (Alliance) identifies primary (1_) side-related angiogenic drivers of metastatic colorectal cancer (mCRC))</h3><h3><br /></h3><h3>459PD 局部进展期直肠癌术后卡培他滨/奥沙利铂对比卡培他滨单药同步放化疗的一项多中心随机对照3期研究的长期随访结果(Long-term Results of Postoperative Chemoradiation Therapy With Capecitabine and Oxaliplatin Versus Capecitabine Alone for Locally Advanced Rectal Cancer: A Randomized, Multicenter, Phase 3 Trial)</h3><h3>该研究来自中国医学科学院肿瘤医院放疗科</h3><h3><br /></h3><h3>460PD II期结肠癌辅助化疗的价值:远比我们想象的少(The value of chemotherapy in Stage II colon cancer: much less than we thought)</h3><h3>该研究来自中国浙江大学医学院第二附属医院消化科</h3><h3><br /></h3><h3>461PD FFCD 1201研究:FOLFOX联合肝动脉内DEBIRI(荷载伊立替康的洗脱微球)一线治疗不可切除结直肠癌肝转移的II期研究(Folfox and intra-arterial DEBIRI as front-line treatment in patients with non resectable colorectal cancer liver metastases (FFCD 1201 phase II trial))</h3><h3><br /></h3><h3>462PD 术后CEA水平与II期结肠癌生存及奥沙利铂辅助化疗获益相关-MOSAIC研究的事后分析(Postoperative carcinoembryonic antigen (CEA) association with survival and oxaliplatin benefit in stage II colon cancer (CC): post hoc analysis of the MOSAIC trial.)</h3><h3><br /></h3><h3>特邀讨论嘉宾:</h3><h3><br /></h3><h3>S. Marsoni教授(456PD, 457PD, LBA24, 458PD),R.A ADAMS教授(459PD, 460PD, 461PD, 462PD)</h3><h3> </h3>